Perbandingan Antivitas Anti-Toksoplasma Ekstrak Jahe Merah (Zingiber Officinale Roscoe. Var. Rubrum), Gingerol dan Shogaol Terhadap Parasit Toxoplasma Gondii Secara In-Vitro

Optimization protocol for the extraction of 6-gingerol and 6-shogaol from Zingiber officinale var. rubrum Theilade and improving antioxidant and anticancer activity using response surface methodology

BACKGROUND Analysis and extraction of plant matrices are important processes for the development, modernization, and quality control of herbal formulations. Response surface methodology is a collection of statistical and mathematical techniques that are used to optimize the range of variables in various experimental processes to reduce the number of experimental runs, cost , and time, compared ...

Optimization of Extraction Conditions for the 6-Shogaol-rich Extract from Ginger (Zingiber officinale Roscoe)

6-Shogaol, a dehydrated form of 6-gingerol, is a minor component in ginger (Zingiber officinale Roscoe) and has recently been reported to have more potent bioactivity than 6-gingerol. Based on the thermal instability of gingerols (their dehydration to corresponding shogaols at high temperature), we aimed to develop an optimal process to maximize the 6-shogaol content during ginger extraction by...

Antiparasitic effects of Zingiber officinale (Ginger) extract against Toxoplasma gondii

In vitro evaluation of anti-Alzheimer effects of dry ginger (Zingiber officinale Roscoe) extract.

As the disease modifying therapies against Alzheimer's disease (AD) continue to exist as a major challenge of this century, the search for newer drug leads with lesser side effects is on the rise. A large number of plant extracts and phytocompounds are being actively pursued for their anti-Alzheimer effects. In the present study, the antioxidant activity, cholinesterase inhibition, anti-amyloid...

Gingerol Fraction from Zingiber officinale Protects Against Gentamicin-

26 Nephrotoxicity is the main complication of gentamicin (GM) treatment. GM induces 27 renal damage by overproduction of reactive oxygen species and inflammation in 28 proximal tubular cells. Phenolic compounds from ginger, called gingerols, have 29 demonstrated to have antioxidant and anti-inflammatory effects. We investigated if the 30 oral treatment with an enriched solution of gingerols (GF...